Do I need a Neutrophils % test?

Do you find yourself catching every cold going around, or wondering why infections seem to linger longer for you? Your neutrophil levels may offer some clues about how well your immune system is responding and protecting you.

Neutrophils % measures the proportion of neutrophils among your total white blood cells, reflecting your body's frontline defence against bacteria, viruses, and other invaders.

Understanding your neutrophil levels can help you make more informed choices about your health and lifestyle. This simple blood marker, included in Listen Health's immune function panel, gives you insight into how your immune system is currently functioning—so you can work towards building the resilience and protection your body needs.

Neutrophils % — Key Facts
MeasuresNeutrophils make up about 60–70% of your white blood cells and are vital for protecting against infection
CategoryImmune Function
Unit%
Tested inListen Health Standard & Premium membership (100+ biomarkers)
Reviewed byDr Jamie Deans, MBChB

What is it?

Neutrophils are the most common type of white blood cell in your blood. They are made in the bone marrow and travel through your bloodstream, ready to fight off bacteria, fungi, and other germs. When your body senses an infection or injury, neutrophils rush to the area to help protect you.

They work by swallowing germs (phagocytosis), releasing chemicals to kill invaders, and forming special traps to catch and destroy harmful microbes. Neutrophils also help clean up damaged tissue and support healing. Scientists have discovered that neutrophils are not all the same—there are different types with unique jobs, including helping with tissue repair and even influencing other immune cells.

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Why does it matter?

Neutrophils make up about 60–70% of your white blood cells and are vital for protecting against infection.

If your neutrophil percentage is higher than normal, it may mean your body is fighting an infection, dealing with inflammation, or responding to stress. High neutrophil levels can also be seen in chronic diseases like heart disease, autoimmune conditions, or cancer. Low neutrophil percentages can make it harder for your body to fight off infections and may be caused by certain medications, bone marrow problems, or viral illnesses. Neutrophils also play a role in allergies, asthma, and healing after injury. Their activity is influenced by your diet, sleep, stress, and even the bacteria living in your gut. Some nutrients, like vitamin B3, protein, and healthy fats, help neutrophils work properly, while deficiencies can make you more likely to get sick.

What causes fluctuations?

  • Infections: Bacterial infections typically increase neutrophil count.

  • Stress and inflammation: Physical or emotional stress can cause short-term elevations.

  • Medications: Steroids, chemotherapy, or antibiotics can lower counts.

  • Autoimmune or bone marrow disorders: May cause low or unstable levels.

Recommendations

  • Strengthen immune defenses: Prioritise nutrient-dense foods high in vitamin C, zinc, and antioxidants.

  • Rest and recovery: Chronic sleep deprivation or overtraining can weaken immune resilience.

  • Address infections early: Seek medical care for unresolved or recurrent infections.

  • Reduce chronic inflammation: A Mediterranean-style diet, regular movement, and stress regulation help maintain balance.

References

  1. Herro, R., & Grimes, H. L. (2024). The diverse roles of neutrophils from protection to pathogenesis. Nature Immunology, 25(12), 2209–2219. https://doi.org/10.1038/s41590-024-02006-5

  2. Siwicki, M., & Kubes, P. (2023). Neutrophils in host defense, healing, and hypersensitivity: Dynamic cells within a dynamic host. The Journal of Allergy and Clinical Immunology, 151(3), 634–655. https://doi.org/10.1016/j.jaci.2022.12.004

  3. Liew, P. X., & Kubes, P. (2019). The neutrophil’s role during health and disease. Physiological Reviews, 99(2), 1223–1248. https://doi.org/10.1152/physrev.00012.2018

  4. Thind, M. K., Uhlig, H. H., Glogauer, M., et al. (2023). A metabolic perspective of the neutrophil life cycle: New avenues in immunometabolism. Frontiers in Immunology, 14, 1334205. https://doi.org/10.3389/fimmu.2023.1334205

  5. Metzemaekers, M., Malengier-Devlies, B., Gouwy, M., et al. (2023). Fast and furious: The neutrophil and its armamentarium in health and disease. Medicinal Research Reviews, 43(5), 1537–1606. https://doi.org/10.1002/med.21958

  6. Fine, N., Tasevski, N., McCulloch, C. A., Tenenbaum, H. C., & Glogauer, M. (2020). The neutrophil: Constant defender and first responder. Frontiers in Immunology, 11, 571085. https://doi.org/10.3389/fimmu.2020.571085

  7. Burn, G. L., Foti, A., Marsman, G., Patel, D. F., & Zychlinsky, A. (2021). The neutrophil. Immunity, 54(7), 1377–1391. https://doi.org/10.1016/j.immuni.2021.06.006

  8. Hellebrekers, P., Vrisekoop, N., & Koenderman, L. (2018). Neutrophil phenotypes in health and disease. European Journal of Clinical Investigation, 48(Suppl 2), e12943. https://doi.org/10.1111/eci.12943

  9. Kumar, S., & Dikshit, M. (2019). Metabolic insight of neutrophils in health and disease. Frontiers in Immunology, 10, 2099. https://doi.org/10.3389/fimmu.2019.02099

  10. Fleming, K., Cornish, N., Vincent, E. E., et al. (2025). A comprehensive phenome-wide analysis of the role of neutrophils in health and disease. Journal of Leukocyte Biology, 117(7), qiaf076. https://doi.org/10.1093/jleuko/qiaf076

  11. Maier-Begandt, D., Alonso-Gonzalez, N., Klotz, L., et al. (2024). Neutrophils—biology and diversity. Nephrology, Dialysis, Transplantation, 39(10), 1551–1564. https://doi.org/10.1093/ndt/gfad266

  12. Wang, X., Qiu, L., Li, Z., Wang, X. Y., & Yi, H. (2018). Understanding the multifaceted role of neutrophils in cancer and autoimmune diseases. Frontiers in Immunology, 9, 2456. https://doi.org/10.3389/fimmu.2018.02456

Frequently Asked Questions

AHPRA Disclaimer: This information is general in nature and should not replace individual medical advice. Always discuss your test results and health concerns with a registered healthcare practitioner.